Anadrol is known (sometimes notoriously) as being one of the contenders for being the strongest oral anabolic steroid commercially available. It closely competes with Dianabol (Methandrostenolone), and steroid-using bodybuilding circles have always debated which of the two are stronger.
One of the unique and mysterious characteristics possessed by Anadrol is that although it is a derivative of DHT, it possesses a very high level of Estrogenic activity. It is typically known that DHT-derivative anabolic steroids should be unable to convert into Estrogen via the aromatase enzyme and therefore elicit no Estrogenic effects, but this is very different with Anadrol. Anadrol is well known for causing water retention, bloating, gynecomastia, and other Estrogenic effects on the body even though it does not convert into Estrogen. It is believed that Anadrol itself acts as an estrogen in certain tissues. This will be further expanded upon and discussed later on, but it is imperative for any potential user to understand that first and foremost that although Anadrol is a DHT-derivative, one will not experience the lean hard gains typically seen with DHT-derivatives. Anadrol is notorious for its Estrogenic effects that cannot be combated with aromatase inhibitors due to its inability to convert into Estrogen.
Anadrol is an orally active anabolic steroid, which means it has been C17 Alpha Alkylated in order to allow the anabolic steroid to make the first pass through the liver without suffering destruction through liver metabolism. Anadrol, however, is very well known for its very harsh hepatotoxicity, which will be explained in greater detail shortly. Anadrol’s chemical modifications and chemical structure (including its C17 Alpha Alkylation) makes it very resistant to hepatic breakdown (liver metabolism). The greater resistance a substance has to hepatic breakdown, the more toxicity and strain on the liver will be experienced – and Anadrol is notorious for its liver toxicity, and is perhaps regarded as the most liver toxic oral anabolic steroid conventionally available.
Because Anadrol is most commonly manufactured in 50mg tablets, bodybuilding and athletic purposes call for 25 – 50mg per day for a beginner. Intermediate users are known for using a range of 50 – 100mg per day, and although approaching risky limits, advanced users as high as 150mg per day. Generally, however, most users whether beginner, intermediate, or advanced, should seldom require more than 50mg per day due to the sheer potency and strength of Anadrol as an anabolic steroid. This is especially the case when studies have demonstrated that a 100mg Anadrol dosage is indeed more effective than a 50mg Anadrol dosage, but beyond 100mg the results will be no more effective than 100mg itself, and diminishing returns begin to manifest.
An additional point of interest about Anadrol dosages is that many users report a reduction in appetite directly proportional to the dose utilized, and studies have shown that it also increases glucose intolerance and insulin resistance, thus making nutrient use by the body less efficient.
Anadrol dosages can and should ideally be split throughout the day so as to ensure stable and steady blood plasma levels of the hormone. Anadrol exhibits a half-life of about 8 to 9 hours in the body, and therefore a schedule involving a morning (AM) dose followed by an afternoon/evening (PM) dose is best.
Anadrol is without question one of the most powerful anabolic steroids on the market. Of all the anabolic steroids available on the prescription market it may be the most powerful of all. This is not a steroid for the faint of heart and is by no means a steroid that should be used by a novice performance enhancing athlete. As we saw in the side effect section, Anadrol can carry quite a few potential adverse effects and you need to understand the hormone as well as proper supplementation practices before you begin a course. However, if this is an anabolic steroid you’re ready to try you will find its ability to pack on lean muscle mass is almost beyond comprehension. Further, when it comes to raw strength and power, this potent anabolic steroid provides an enormous punch.